TABLE 1

Diphosphoinositol polyphosphate metabolism: enzyme nomenclature

There are three IP6K genes: 1, 2, and 3. There are four DIPP genes: 1, 2α, 2β, 3.


HGNC-Approved Gene Name

Catalytic Function

Other Names

S. cerevisiae Homolog
HISPPD2A Kinase (and phosphatase?a) VIP1PPIP5K1 Vip1
HISPPD1 Kinase (and phosphatase?a) VIP2PPIP5K2
IP6K# Kinase IHPK# Kcs1
NUDT#
Phosphatase
DIPP#
Ddp1
  • a The protein has an “acid phosphatase”-like domain, but no catalytic activity has been reported.