TABLE 6

Behavioral effects induced by long-term treatment with fluoxetine and/or Δ9-THC in OBX animals assessed in the open-field test

Data represent mean ± S.E.M.

Ambulation Scores
Vehicle-sham70.3 ± 7.5
Vehicle-OBX152.3 ± 15.3***
Fluoxetine-treated OBX99.1 ± 9.5#
Fluoxetine + THC-treated OBX101.7 ± 12.2#
THC-treated OBX151.3 ± 18.2***

  • F = 7.8, p < 0.001 (ANOVA).

  • ↵*** p < 0.001 versus vehicle-sham rats.

  • ↵# p < 0.05 versus vehicle-OBX rats (Newman-Keuls post-ANOVA).