TABLE 5

IPA analysis of genes associated with canonical pathways significantly modulated by AHR activation

Top IPA Canonical PathwaysPRatio
Aryl hydrocarbon receptor signaling1.76 × 10−45/155 (0.032)
Xenobiotic metabolism signaling1.91 × 10−46/254 (0.024)
Virus entry via endocytic pathways2.96 × 10−44/96 (0.042)
Glucocorticoid receptor signaling3.33 × 10−46/278 (0.022)
PPARα/RXRα activation3.92 × 10−45/185 (0.027)
  • PPAR, peroxisome proliferator-activated receptor; RXR, retinoid X receptor.