TABLE 1

Na/K-ATPase inhibitors identified by high-throughput screen

These inhibitors produced at least 25% inhibition of Na/K-ATPase at 10 μg/ml.

SampleNameFormula
2006BD3Metacycline hydrochlorideC22H22N2O8.HCl
2008BB8TyrothricinMixture
2018BF7MyricetinC15H10O8
2021BG2Domiphen bromideC22H40NO.Br
2035BD1ResibufogeninC24H32O4
2035BA5CinobufaginC26H34O6
2036BF1OligomycinC45H74O11
MB11,3-DihydroxyxanthoneC13H8O4
MB23,4-DihydroxyxanthoneC13H8O4
MB31,3,5-TrihydroxyxanthoneC13H8O5
MB53,4,5-TrihydroxyxanthoneC13H8O5
MB61,3,5,6-TetrahydroxyxanthoneC13H8O6
MB73,4,5,6-TetrahydroxyxanthoneC13H8O6