Difference in the positions of the secondary structure elements in the N-terminal domain in three homology models of the human UGT1A1
The averages are calculated from unsigned differences; “average” values are those calculated without helix Nα3.
| Source | Nβ1 | Nα1 | Nβ2 | Nα2 | Nβ3 | Nα3 | Nβ4 | Nα4 | Nβ5 | Nβ6 | Nα6 | Nβ7 | Average/“Average” |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Li and Wu, 2007; current study | 0 | 0 | −2 | −4 | −5 | +19 | 0 | 0 | 0 | +8 | +7 | 0 | 3.75/2.36 |
| Locuson and Tracy, 2007; current study | 0 | 0 | −2 | −9 | 0 | +4 | 0 | 0 | 0 | −1 | −4 | −1 | 1.75/1.54 |
| Li and Wu, 2007/Locuson and Tracy, 2007 | 0 | 0 | 0 | +5 | +5 | +15 | 0 | 0 | 0 | +9 | +11 | +1 | 3.83/2.82 |