TABLE 1

Basal mean arterial pressure and heart rate in WT and Sp(−/−) mice

Mean arterial pressure (MAP) and heart rate (HR) was measured in awake, freely moving WT and Sp(−/−) mice as described under Materials and Methods. Values represent mean ± S.E.M.; n = 5 for each genotype.

GenotypeMAP (mm Hg)HR (beat/min)
WT103 ± 1.6598 ± 32
Sp(−/−)101 ± 2.5632 ± 12