Ki values ± S.E.M. of peptide inhibitors for phenylalanine-544 substituted IRAP
| Nle1-Ang IV | Ang IV | LVV-H7 | |
|---|---|---|---|
| μM | |||
| IRAP | 0.23 ± 0.05 | 0.15 ± 0.01 | 0.36 ± 0.04 |
| [F544I]IRAP | 7.85 ± 1.34 | 0.21 ± 0.03 | 0.72 ± 0.04 |
| [F544V]IRAP | 1.02 ± 0.33 | 0.18 ± 0.03 | 0.83 ± 0.20 |
Nle1-Ang IV, NleYIHPF; Ang IV, VYIHPF; LVV-H7, LVVYPWTQRF.