TABLE 1

Rate of FTY720 and AAL(R) phosphorylation in whole blood

Phosphorylation rates were calculated using only the linear portion of the phosphorylation curves shown in Fig. 3B. Data are presented as mean ± S.E.

BloodFTY720AAL(R)
nmol product/h/ml of blood
Human0.056 ± 0.0010.496 ± 0.014
Rat1.93 ± 0.04013.3 ± 1.13