TABLE 4

Transduction ratios for norepinephrine and epinephrine at the α1A-AR

LogTR is the log of the transduction ratio (τ/KA), and logTRn values are normalized to the logTR for norepinephrine.

AgonistCa2+ Release (n = 9)cAMP (n = 7)ECAR (n = 8)
logTRlogTRnlogTRlogTRnlogTRlogTRn
Norepinephrine8.78 ± 0.090.00 ± 0.165.59 ± 0.080.00 ± 0.127.49 ± 0.090.00 ± 0.13
Epinephrine9.33 ± 0.080.55 ± 0.165.78 ± 0.080.19 ± 0.127.94 ± 0.090.45 ± 0.12