Compounds used in this study
Histamine receptor agonists and antagonists used, with receptor subtype selectivity.
| Compound | Receptor Subtype | Mode of Action |
|---|---|---|
| Histamine | All | Agonist |
| 2-PED | H1 | Agonist |
| Triprolidine | H1 | Selective antagonist |
| Mepyramine | H1 | Selective antagonist |
| Ranitidine | H2 | Selective antagonist |
| Clobenpropit | H3 | Selective antagonist |
| H4 | Reduced efficacy agonist | |
| Thioperamide | H3 | Antagonist |
| H4 | Inverse agonist | |
| JNJ7777120 | H4 | Selective antagonist |