ATP concentration response data
| Channel | EC50 | pEC50 | Hill Slope |
|---|---|---|---|
| μM | |||
| WT BmP2X | 67.1 | 4.17 ± 0.03 | 1.5 ± 0.03 |
| BmP2X M362L | 117.5 | 3.93 ± 0.03 | 2.7 ± 0.03 |
| HdP2X | 25.5 | 4.59 ± 0.04 | 1.2 ± 0.01 |
| Chimera A | 100.2 | 4.00 ± 0.06 | 1.0 ± 0.12 |
| Chimera B | 34.8 | 4.46 ± 0.07 | 0.9 ± 0.11 |
| Chimera C | 5.2 | 5.29 ± 0.05 | 0.7 ± 0.06 |
| Chimera D | 12.1 | 4.92 ± 0.06 | 0.5 ± 0.04 |
| Chimera E | 7.2 | 5.14 ± 0.06 | 1.1 ± 0.13 |
| Chimera F | 6.9 | 5.16 ± 0.04 | 0.8 ± 0.05 |