TABLE 2

Effects of (−)-CM-TPMF and (−)-B-TPMF at hKCa2 channels in inside out experiments

(−)-CM-TPMF(−)-B-TPMF
EC50aHill SlopeIC50bHill Slope
μMμM
hKCa2.10.0240.80.031−1.2
hKCa2.20.291.51.05−1.7
hKCa2.30.251.11.32−1.7
hKCa2.3L476S0.031.20.05−1.6
  • a At 0.2 μM [Ca2+]i.

  • b At 0.5 μM [Ca2+]i.