Basal extracellular 5-HT levels in the DR in vehicle/vehicle; vehicle/fluoxetine, corticosterone/vehicle, and corticosterone/fluoxetine groups of mice. Data are the mean ± S.E.M. calculated from four baseline samples. n = 4–6 mice per group.
| Pretreatment | Treatment | Basal [5-HT]ext in the DR |
|---|---|---|
| fmol | ||
| Vehicle (β-CD 0.45%) | Vehicle | 13.4 ± 4.1 |
| Vehicle (β-CD 0.45%) | Fluoxetine (18 mg/kg/day) | 75.9 ± 3.1*** |
| Corticosterone (35 μg/ml/day) | Vehicle | 14.8 ± 3.6 |
| Corticosterone (35 μg/ml/day) | Fluoxetine (18 mg/kg/day) | 114.9 ± 24.1** |