Agonist | + 50 μM 2-APB | +100 nM PTX | ||||||
---|---|---|---|---|---|---|---|---|
293TR SNAP-GPR120S | 293TR SNAP-GPR120L | 293TR SNAP-GPR120S | 293TR SNAP GPR120L | |||||
pEC50 | Rmax | pEC50 | Rmax | pEC50 | Rmax | pEC50 | Rmax | |
% | % | % | % | |||||
ATP | 5.3 ± 0.2 | 89 ± 5 | 5.2 ± 0.1 | 81 ± 10 | 5.2 ± 0.1 | 92 ± 2 | 5.4 ± 0.1 | 94 ± 8 |
OA | 4.5 ± 0.2 | 50 ± 13 | 20 ± 4 | 4.6 ± 0.2 | 49 ± 3 | 10 ± 2 | ||
Myr | 5.0 ± 0.2 | 57 ± 9 | 9 ± 5 | 4.8 ± 0.2 | 53 ± 9 | 7 ± 2 | ||
GW9508 | 5.2 ± 0.2** | 107 ± 11 | 37 ± 17 | 5.2 ± 0.1* | 107 ± 5 | 30 ± 14 |