TABLE 2

IC50 values of PCNA-Is

The growth-inhibitory effects of the compounds were determined by the MTT assay, and IC50 values were derived from growth-inhibitory curves as detailed in the legend to Table 1. Data shown are the mean of two independent experiments.

PCNA-IsPC-3LNCaP
μM
PCNA-I30.440.26
PCNA-I43.000.68
PCNA-I6>10.0>10.0
PCNA-I73.602.20
PCNA-I81.000.68
PCNA-I92.200.71
PCNA-I10>10.02.20