Calcium Channel | V0.5 act | Erev | Gmax | Vh | IC50 Tonic |
---|---|---|---|---|---|
mV | nS | mV | μM | ||
hCav3.2 | −44.3 ± 1.4 (n = 7) | 27.3 ± 0.7 (n = 7) | −1.9 ± 0.08 (n = 7), N.S. | −64.2 ± 0.93 (n = 5), N.S. | 7.0 ± 0.51 (n = 6) |
hCav3.2 I403A | −54.0 ± 1.8 (n = 11)* | 20.3 ± 1.8 (n = 11)* | −1.7 ± 0.09 (n = 11), N.S. | −63.8 ± 0.87 (n = 6), N.S. | 20.0 ± 1.5 (n = 6)** |
hCav3.2 V1551A | −47.0 ± 1.1 (n = 13), N.S. | 23.8 ± 1.5 (n = 13), N.S. | −1.9 ± 0.06 (n = 13), N.S. | −67.0 ± 0.98 (n = 6), N.S. | 40.0 ± 3.1 (n = 6)** |
hCav3.2 V1855Y | −29.64 ± 2.1 (n = 14) | 14.64 ± 2.1 (n = 14) | −3.9 ± 0.14 (n = 14) | −58.4 ± 0.56 (n = 6) | 1.8 ± 0.41 (n = 6)* |