Single-channel conductance
Data are means ± S.E.M. The frequency of the three conductance classes was calculated as a weighted mean ± S.E.M., based on the number of openings in each patch.
| Agonist | Conductance 1 [Frequency] | Conductance 2 [Frequency] | Conductance 3 [Frequency] |
|---|---|---|---|
| pS [%] | |||
| ACh (n = 9) | 32.7 ± 3.3 [2.8 ± 2.9] | 63.6 ± 2.7 [5.2 ± 2.9] | 90.0 ± 2.7 [92.0 ± 12.9]‡ |
| ACh + TQS (n = 14) | 47.0 ± 4.6 [14.0 ± 2.0]* | 81.1 ± 5.1 [33.4 ± 4.4] | 109.4 ± 5.5 [52.4 ± 7.0]** |
| 4BP-TQS (n = 20) | 40.0 ± 2.4 [8.5 ± 2.6] | 67.6 ± 3.7 [12.7 ± 2.9] | 100.3 ± 2.4 [78.7 ± 5.2]† |
| ACh + 4BP-TQS (n = 8) | 40.6 ± 2.6 [6.3 ± 2.2] | 63.9 ± 6.6 [18.9 ± 1.9] | 107.3 ± 2.8 [74.8 ± 2.3]* |
↵Significant differences in conductance (determined by ANOVA) to ACh (* P < 0.05; ** P < 0.01) are indicated. Otherwise, significant differences determined by pairwise comparisons to ACh († P < 0.05) or to 4BP-TQS (‡ P < 0.05) are indicated.