TABLE 2

HeLa cell cytotoxicity and specificity index for parasite killing

PSAC InhibitorHeLa Cell CC50Specificity (HeLa Cell CC50/Parasite PGIM IC50)
μM
130110
9>100>430
2>100>240
TP-52>100>530
5>100>50
ISG-218643,000
  • CC50, concentration of inhibitor that reduced conversion of MTS to formazan by 50%.