TABLE 2

Structure of compounds with agonistic properties at the WT human P2Y12

BackboneSubstancesSide Chain
R1R2R3R4R5
Embedded ImageADPHOHOHOOH
ADPβSHOHOHSOH
TNP-ADPHC6N3O8H4OOH
AppNH2HOHOHONH2
ATPHOHOHOPO4H2
ATPγSHOHOHOPSO3H2
2I-ATPγSIOHOHOPSO3H2