Agonists | mFpr1 | mFpr2 | ||
---|---|---|---|---|
EC50 (M) | MaxE | EC50 (M) | MaxE | |
fMLF | 2.3 ± (2.7) × 10−5 | 2.6 ± 0.2 | ND | ND |
fMLFE | 6.7 ± (1.1) × 10−9 | 3.6 ± 0.4 | ND | ND |
fMLFK | 5.1 ± (1.0) × 10−7 | 3.6 ± 0.3 | 2.3 ± (.67) × 10−6 | 3.0 ± 0.3 |
fMLFW | 1.1 ± (.16) × 10−9 | 4.6 ± 0.3 | 3.3 ± (.45) × 10−6 | 3.1 ± 0.3 |
fMIFL | 3.5 ± (.46) × 10−10 | 4.8 ± 0.4 | 5.3 ± (2.6) × 10−4 | 1.7 ± 0.2 |
fMLFII | 3.1 ± (.32) × 10−11 | 4.8 ± 0.3 | 9.1 ± (3.7) × 10−7 | 3.3 ± 0.2 |
fMLFIIK | 4.6 ± (1.1) × 10−10 | 3.4 ± 0.1 | 9.0 ± (7.4) × 10−7 | 3.7 ± 0.1 |
fMIVTLF | 2.1 ± (.45) × 10−11 | 4.7 ± 0.4 | 2.8 ± (.55) × 10−6 | 2.6 ± 0.1 |
fMMYALF | 9.8 ± (4.2) × 10−11 | 4.1 ± 0.2 | 4.7 ± (3.1) × 10−6 | 2.4 ± 0.4 |
WKYMVm | 8.2 ± (1.9) × 10−11 | 4.6 ± 0.3 | 4.5 ± (1.2) × 10−10 | 4.0 ± 0.2 |
Quin C1 | 2.4 ± (.33) × 10−6 | 4.4 ± 0.2 | 6.3 ± (.92) × 10−7 | 3.6 ± 0.3 |
Compound 43 | 1.9 ± (.25) × 10−9 | 4.4 ± 0.4 | 1.2 ± (.17) × 10−7 | 3.0 ± 0.3 |
ND, not determined.