WT | C201A | C208A | C242A | |
---|---|---|---|---|
−logIC50 ± S.E.M. | ||||
NAM | 6.06 ± 0.12 | Ambiguous | 6.51 ± 0.10 | 6.34 ± 0.06 |
MAFP | 7.69 ± 0.11 | 7.79 ± 0.05 | 7.59 ± 0.20 | 6.08 ± 0.80* |
JZL184 | 6.19 ± 0.12 | 5.81 ± 0.04 | 6.70 ± 0.11** | 5.74 ± 0.06** |
JJKK-048 | 9.39 ± 0.04 | 9.38 ± 0.02 | 9.59 ± 0.07 | 9.01 ± 0.06*** |
IDFP | 9.36 ± 0.22 | 9.42 ± 0.20 | 9.58 ± 0.34 | 7.55 ± 0.06*** |
Pristimerin | 5.36 ± 0.20 | 5.37 ± 0.05 | 5.33 ± 0.41 | 5.60 ± 0.08 |
↵* P < 0.001; **P < 0.05; ***P < 0.01.