Brain Region | [3H]Epi | [125I]-α-Bgtx |
---|---|---|
fmol/mg protein | ||
Basal forebrain | 31.8 ± 8.5 | 80.7 ± 7.0 |
Cerebellum nonsmokers | 22.5 ± 2.6 | 45.7 ± 5.1 |
Cerebellum smokers | 39.7 ± 5.3* | 48.3 ± 6.5 |
↵* P = 0.02 (significant differences in cerebellar membrane [3H]Epi binding between smokers and nonsmokers: unpaired t test). No significant difference was seen between [125I]-α-Bgtx binding levels in cerebellar samples taken from smokers versus nonsmokers, by the same measure.