Summary of signaling data for wild-type RSPOs1–4 Fu1–Fu2
Emax values are % of MBP-Th-RSPO2. The number of observations is indicated in parentheses.
| R-spondin | pEC50 ± S.E.M. | Emax ± S.E.M. |
|---|---|---|
| MBP-Th-RSPO1 | 8.82 ± 0.15** (3) | 88.82 ± 5.05 (3) |
| MBP-Th-RSPO2 | 9.62 ± 0.11 (3) | 100 (3) |
| MBP-Th-RSPO3 | 9.56 ± 0.06 (3) | 101.2 ± 1.39 (3) |
| MBP-Th-RSPO4 | 9.95 ± 0.16 (3) | 67.85 ± 1.07*** (3) |
↵** P < 0.01; ***P < 0.001 versus MBP-Th-RSPO2 by one-way ANOVA with Tukey’s multiple comparison test.