TABLE 3

Comparison of OA transporter genes detected in human ciliary body in this study to three previously published studies

The gene expression data from this study were taken from Fig. 1. The study by Dahlin et al. (2013), as in the present study, used ciliary body, whereas the studies by Chen et al. (2013) and Zhang et al. (2008) used iris-ciliary body preparations. Although Dahlin et al. (2013) examined the expression of other transporters they only reported data for the 10 most highly expressed TransPortal (http://bts.ucsf.edu/fdatransportal) transporter genes identified in their study. The six shown were also examined by us.

TransporterThis StudyDahlin et al. (2013)Zhang et al. (2008)Chen et al. (2013)
OAT1DetectedDetected
OAT2Not detectedNot detected
OAT3DetectedDetected
OATP1A2Detected (weak signal)DetectedNot detected
OATP1B1Not detectedNot detected
OATP1B3Not detectedDetectedNot detected
OATP2B1DetectedDetected
MRP2DetectedNot detectedDetected
MRP3DetectedDetectedNot detected
MRP4DetectedDetectedDetected
MRP5DetectedDetectedDetected
MRP7DetectedDetected
BCRPDetected (weak signal)DetectedDetectedDetected
PgpDetectedDetectedDetectedDetected
  • The em dash (—) indicates that the expression of the transporter gene was not reported or was not examined.