Initial Zn2+ ion flux into DOPC liposomes
Fluxes were calculated from linear fits of initial fluorescence changes in the time-courses represented in Fig. 2 using eq. 1. Values are mean ± S.D. (n ≥ 3).
| Sample | Ji (mol m−2 s−1) (10−14) |
|---|---|
| ZnCl2 only (10 μM) | 8.90 ± 0.94 |
| ZnCl2 + DMSO (0.2%) | 6.81 ± 0.68 |
| ZnCl2 + ZMC1 (1 μM) | 52.3 ± 1.2 |
| ZnCl2 + ZMC1 (5 μM) | 135 ± 5 |
| ZnCl2 + NTA (5 μM) | 4.52 ± 1.22 |
| ZnCl2 + A6 (5 μM) | 71.3 ± 2.9 |
| EDTA Only (100 μM) | −0.69 ± 0.67 |
| EDTA + DMSO (0.2%) | −0.53 ± 1.43 |
| EDTA + ZMC1 (1 μM) | −131 ± 2 |
| EDTA + ZMC1 (5 μM) | −199 ± 86 |