TABLE 1
p
K
i
values from standard fit
Compound
p
K
i-GTP coupling
(95% CI)
p
K
i-
β
arr2 recruitment
(95% CI)
6′-GNTI
8.9 (9.1 to 8.6)
8.1 (8.8 to 7.3)
Nalbuphine
7.0 (7.3 to 6.7)
6.6 (6.7 to 6.5)
Nalmefene
8.7 (9.5 to 7.9)
8.1 (8.2 to 8.0)