TABLE 5

∆LogRA values from the standard fit

Compound∆LogRA(GTP coupling –βarr2 recruitment) (95% CI)Bias FactorStandard
U69,59301.0
6′-GNTI1.0 (0.6 to 1.4)10
Nalbuphine0.5 (0.006 to 1.0)3.2
Nalmefene0.9 (−0.3 to 2.0)7.9