TABLE 2

LogRA values from the standard fit

CompoundLogRAGTP coupling (95% CI)LogRAβarr2 recruitment (95% CI)
U69,59300
6′-GNTI1.3 (1.1 to 1.6)0.3 (−0.2 to 0.9)
Nalbuphine−0.9 (−1.2 to −0.5)−1.3 (−1.5 to −1.1)
Nalmefene0.3 (−0.5 to 1.2)−0.6 (−0.7 to 0.4)