TABLE 1

Comparison of the effect of COH29 in several cell lines

BRCA1Cell LineIC50 of COH29
µM
Wild-typeOV9031.57 ± 3.35
MutantUWB1.28912.30 ± 1.25
UWB1.289/BRCA123.52 ± 2.38
MutantHCC19377.25 ± 0.64
HCC1937/BRCA135.01 ± 3.63