TABLE 1

Unique pig residues within the VFT subdomain of the pCaSR ECD

Human, dog and rat CaSR sequences were obtained from the public database (NCBI: http://www.ncbi.nlm.nih.gov/homologene/332.

Amino Acid Residues
PositionHumanDogRatPig
50AspartateAspartateAspartateGlutamate
52LysineLysineLysineGlutamate
340ArginineArginineArginineSerine
369ProlineSerineProlineThreonine
370ValineMethionineValineThreonine
438LeucineLeucineLeucineIsoleucine
471AsparagineAsparagineAsparagineSerine
482CysteineCysteineCysteineTyrosine
486ValineMethionineValineAlanine