HT29 cell levels of cytotoxicity after 24-hour incubation in culture medium with vehicle, AqB011, or HgCl2
| Agent (AqB011) | Mean Normalized Cell Viability ± S.E.M.a | n Value | Statistical Significance |
|---|---|---|---|
| μM | % | ||
| 0 (untreated) | 100.0 ± 0.70 | 8 | — |
| 0 (0.1% DMSO) | 103.9 ± 0.91 | 8 | N.S. |
| 1 | 104.0 ± 1.06 | 4 | N.S. |
| 5 | 102.3 ± 2.26 | 4 | N.S. |
| 10 | 110.6 ± 2.12 | 4 | N.S. |
| 20 | 114.0 ± 0.84 | 4 | N.S. |
| 40 | 111.8 ± 1.33 | 4 | N.S. |
| 80 | 102.4 ± 2.95 | 4 | N.S. |
| HgCl2 (100 μM) | 16.2 ± 0.20 | 3 | ** |
↵a Percent viability was standardized as a percentage of the untreated mean value measured as changes in alamarBlue fluorescence signal intensity. See Materials and Methods for details.