TABLE 1

Summary of fitted curve parameters for results shown in Figs. 1 (Gαi activity), 5 (β-arrestin recruitment), and 8 (ERK1/2 phosphorylation).

pEC₅₀ values are given and maximal responses are shown in absolute (β-arrestin recruitment) and relative (ERK1/2 phosphorylation and Gαi activity) units. Errors are presented as ± S.E.M.

	CXCR3A		CXCR3B
	CXCL11	CXCL10	CXCL11
cAMP inhibition
N	4	4	6
IC₅₀ (nM)	0.7	0.5	N.D.
pIC₅₀ ± S.E.M.	−9.5 ± 0.3	−9.4 ± 0.2	N.D.
E_max ± S.E.M.	89 ± 11	70 ± 7	N.D.
β-arrestin2
N	3	3	3
EC₅₀ (nM)	8	71	61
pEC₅₀ ± S.E.M.	−8.2 ± 0.1	−7.3 ± 0.2	−7.2 ± 0.1
BRET²_max ± S.E.M.	0.11 ± 0.01	0.07 ± 0.01	0.026 ± 0.001^a
β-arrestin1
N	3	3	3
EC₅₀ (nM)	16	32	33
pEC₅₀ ± S.E.M.	−7.8 ± 0.1	−7.5 ± 0.1	−7.6 ± 0.2
BRET²_max ± S.E.M.	0.06 ± 0.01^α	0.025 ± 0.003^α	0.01 ± 0.001
ERK1/2 phosphorylation
N	4	4	6
EC₅₀ (nM)	2	3	N.D.
pEC₅₀ ± S.E.M.	−8.9 ± 0.1	−8.5 ± 0.1	N.D.
E_max ± S.E.M.	368 ± 32	293 ± 32	N.D.

↵^a Theoretical value, experimental curves did not reach saturation.
N.D., not detectable.