Cellular sensitivity (EC50) to the four TSC compounds of the results shown in Fig. 2A
| ZMC1 | ZMC2 | ZMC3 | 3-AP | |
|---|---|---|---|---|
| µM | µM | µM | µM | |
| TOV112D (p53R175H) | 0.087 | 0.087 | 3.373 | 1.644 |
| SKBR3 (p53R175H) | 0.009 | 0.009 | 2.061 | >10 |
| HOP92 (p53R175L) | 0.291 | 0.168 | 1.807 | 4.246 |
| H1299 (p53 null) | >2 | >2 | >10 | 9.661 |
| H460 (p53 wt) | >2 | >2 | >10 | >10 |