Agonist | logα | logβ | pKA | pKB | N |
---|---|---|---|---|---|
AH-7614 | |||||
TUG-891 | −0.80 ± 0.11 | −0.77 ± 0.09 | 6.77 ± 0.14 | 7.98 ± 0.24 | 4 |
TUG-1197 | −0.52 ± 0.09 | −1.08 ± 0.10 | 6.44 ± 0.05 | 7.82 ± 0.26 | 5 |
GSK137647A | −0.58 ± 0.09 | −1.54 ± 0.14 | 6.32 ± 0.04 | 8.14 ± 0.21 | 3 |
Cpd A | −0.80 ± 0.14 | −0.66 ± 0.15 | 6.31 ± 0.22 | 8.17 ± 0.26 | 3 |
TUG-1506 | |||||
TUG-891 | −1.68 ± 0.17 | −0.18 ± 0.10 | 6.79 ± 0.11 | 7.46 ± 0.06 | 4 |
TUG-1197 | −0.48 ± 0.12 | −1.34 ± 0.13 | 6.48 ± 0.08 | 6.90 ± 0.04 | 3 |
GSK137647A | −0.44 ± 0.07 | −1.24 ± 0.11 | 6.44 ± 0.03 | 7.04 ± 0.10 | 3 |
Cpd A | −2.15 ± 0.36 | 0.06 ± 0.11 | 6.46 ± 0.18 | 7.28 ± 0.02 | 3 |