TABLE 1

Average peak calcium transient measures following the application of nicotine (Nic, 50 μM), ACh (50 μM), or α-Bgtx (Bgtx, 50 nM)

PNU120596 (1 μM) was coapplied.

DrugΔF/Fθ
Nic705.52% ± 89.91%
Nic + Bgtx462.35% ± 83.15%
Nic + PNU1205962286.88% ± 429.91%
Nic + PNU120596 + Bgtx437.01% ± 76.68%
ACh520.61% ± 85.85%
ACh + PNU1205961702.21% ± 302.48%
ACh + PNU120596 + Bgtx888.96% ± 392.74%