Channel | VU0134992 | Amitriptyline | Nortriptyline | Fluoxetine |
---|---|---|---|---|
Kir1.1 | Inactive | 33.0 (16%, 58%) | 31.0 (6%, 50%) | 27.0 (6%, 30%) |
Kir2.1 | Inactive | 35.0 (1%, 36%) | Inactive | 10.1 (10%, 86%) |
Kir2.2 | Inactive | 41.7 (2%, 41%) | Inactive | Inactive |
Kir2.3 | 13.2 (73%) | 21.3 (53%, 89%) | 19.4 (60%, 91%) | 7.1 (98%, 100%) |
Kir3.1/3.2 | 2.5 (92%) | 13.6 (73%, 91%) | 16.1 (65%, 87%) | 3.4 (97%, 100%) |
Kir3.1/3.4 | 3.1 (92%) | 12.0 (67%, 88%) | 15.0 (56%, 80%) | 2.4 (94%, 100%) |
Kir4.1 | 5.2 (100%) | 89.0 (0%, 66%) | 41.7 (10%, 93%) | 31.2 (35%, 95%) |
Kir4.2 | 8.1 (100%) | 42.7 (0%, 45%) | 46.7 (0%, 65%) | 20.2 (98%, 99%) |
Kir6.2/SUR1 | 11.4 (12%) | 32.2 (4%, 64%) | 42.0 (0%, 52%) | 64 (4%, 65%) |
Kir7.1 | 34.2 (15%) | 22.9 (65%, 89%) | 26.0 (50%, 82%) | 5.8 (75%, 92%) |