TABLE 2

Optimal concentration and percentages for maximizing a reduction in cell viability

		Compound 1		Compound 2		Compound 3		Predicted Decrease in % Cell Viability	95% Confidence Interval	Lack of Fit Prob > F^*
	Combination	Percentage of IC₅₀	Concentration	Percentage of IC₅₀	Concentration	Percentage of IC₅₀	Concentration	Predicted Decrease in % Cell Viability	95% Confidence Interval	Lack of Fit Prob > F^*
1	DOC, CAB, PIP	33	15 nM	67	27 nM	0	0 µM	45	39, 52	0.7069
2	DOC, CAB, FLAV	0	0 nM	33	13 nM	67	108 nM	52	45, 59	0.5903
3	FLAV, MIT, CAB	55	89 nM	44	176 nM	1	0.4 nM	56	44, 69	0.2957
4	FLAV, PIP, CAB	54	86 nM	0	0 µM	46	18 nM	61	46, 76	0.9568
5	FLAV, PIP, MIT	56	90 nM	0	0 µM	44	175 nM	58	40, 76	0.9961
6	PIP, MIT, CAB	0	0 µM	100	400 nM	0	0 nM	55	35, 75	0.5780
7	RES, FLAV, CAB	0	0 µM	73	117 nM	27	11 nM	56	48, 63	0.8182
8	RES, FLAV, MIT	0	0 µM	0	0 nM	100	400 nM	61	46, 76	0.9841
9	RES, FLAV, PIP	0	0 µM	100	160 nM	0	0 µM	50	36, 65	0.9657
10	RES, MIT, CAB	0	0 µM	100	400 nM	0	0 nM	58	44, 72	0.5081
11	RES, PIP, CAB	0	0 µM	0	0 µM	100	40 nM	54	43, 65	0.4811
12	RES, PIP, MIT	0	0 µM	0	0 µM	100	400 nM	58	44, 73	0.9852

↵* Values less than or equal to 0.10 indicate that the model does not fit the data.