TABLE 1
Kinetics of OCT2-mediated transport for the six test substrates
Substrate
K
tapp
±S.E.
J
max
±S.E.
n
μ
M
pmol/cm
2
per minute
Metformin
285.2
67.5
656.2
42.0
3
MPP
4.6
1.5
17.2
1.5
3
NBD
8.8
2.1
33.2
1.6
3
TEA
57.7
18.3
99.9
10.1
2
Cimetidine
15.1
3.5
18.9
0.7
2
ASP
37.6
21.0
51.1
8.5
8