Baseline hemodynamics parameters
Values are represented as the mean ± S.D. The numbers in parentheses are sample size.
| WT | HCN1 KO | |
|---|---|---|
| Body weight, g | 24 ± 3.8 (12) | 25 ± 3.1 (12) |
| Baseline HR, beats/min | 560.1 ± 27.4 (12) | 519.2 ± 24.9 (12)* |
| R-R intervals, ms | 109.2 ± 10.0 (5) | 122 ± 10.5 (5)* |
| SDNN, ms | 13.1 ± 1.4 (5) | 20.4 ± 1.6 (5)* |
| RMSSD, ms | 7.4 ± 1.7 (5) | 18.1 ± 1.5 (5)* |
| SBP, mmHg | 129.2 ± 11.4 (12) | 131.0 ± 7.6 (12) |
| S.D. SBP 24 h, mmHg | 5.8 ± 0.6 (6) | 5.4 ± 0.6 (6) |
| DBP mmHg | 87.4 ± 8.0 (12) | 85.7 ± 8.3 (12) |
| S.D. DBP 24 h, mmHg | 6.4 ± 0.7 (6) | 5.3 ± 0.8 (6) |
| MAP, mmHg | 98.7 ± 6.6 (12) | 103.1 ± 7.3 (12) |
| S.D. MAP 24 h, mmHg | 6.0 ± 0.7 (6) | 5.3 ± 0.7 (6) |
SDNN, S.D. of all normal R-R intervals.
↵* P < 0.05 vs. WT.