Regular ArticleCharacterization and Chromosomal Localization of the Human A2a Adenosine Receptor Gene: ADORA2A
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2010, Journal of Psychiatric ResearchCitation Excerpt :Accordingly, the corresponding gene (ADORA2A, NM_000675) is discussed as a promising candidate for increased anxiety. ADORA2A is located on chromosome 22q11.23 and has two coding exons spanning about 9 kb (MacCollin et al., 1994; Peterfreund et al., 1996; Le et al., 1996). Mutation screening of these exons revealed several variants (Deckert et al., 1998, 2001) of which SNP rs5751876 (1976C/T) was associated or linked with PD (Deckert et al., 1998; Hamilton et al., 2004).
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