Elsevier

Methods

Volume 22, Issue 1, September 2000, Pages 107-114
Methods

Regular Article
In Vitro Selected Oligonucleotides as Receptors in Binding Assays

https://doi.org/10.1006/meth.2000.1041Get rights and content

Abstract

This paper describes a new binding assay that uses oligodeoxyribonucleotides (DNAs) obtained by the in vitro selection method instead of antibodies. DNAs that specifically bound to a target molecule were selected, labeled with some probes, and then used to detect the target molecule by staining or competitive binding assay.

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