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Histamine in Inflammation pp 11–19Cite as

Molecular Pharmacology of the Four Histamine Receptors

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 709))

Abstract

Histamine and its receptors have been (and are still today) very fruitful topics for pharmacological and medicinal chemistry studies. In this chapter we review the various selective ligands that are available for the four different histamine receptors and we describe the main molecular pharmacological aspects of each of the receptor subtypes.

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Authors and Affiliations

  1. Leiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Faculty of Sciences, VU University, Amsterdam, De Boelelaan 1083, 1081 HV, Amsterdam, The Netherlands

    Rob Leurs

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  1. Gerold Bongers
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  2. Iwan de Esch
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  3. Rob Leurs
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Correspondence to Rob Leurs .

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  1. Johnson & Johnson Pharmaceutical Research & Development, LLC, San Diego, California, USA

    Robin L. Thurmond PhD

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Bongers, G., de Esch, I., Leurs, R. (2010). Molecular Pharmacology of the Four Histamine Receptors. In: Thurmond, R.L. (eds) Histamine in Inflammation. Advances in Experimental Medicine and Biology, vol 709. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-8056-4_2

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