Research paperThe role of drug accumulation in 4-aminoquinoline antimalarial potency: The influence of structural substitution and physicochemical properties☆
References (31)
- et al.
Uptake of 3H chloroquine by drug-sensitive and -resistant strains of the human malarial parasite Plasmodium falciparum
Biochem Pharmacol
(1986) - et al.
Lysosomotropic agents
Biochem Pharmacol
(1974) - et al.
Alkalinisation of the food vacuole of malaria parasites by quinoline containing drugs and alkylamines is not correlated with their antimalarial activity
Biochem Pharmacol
(1989) - et al.
Kinetic modelling of the response of Plasmodium fakiparum to chloroquine and its experimental testing in vitro. Implications for mechanism of action and resistance to the drug
Biochem Pharmacol
(1990) - et al.
A perspective on antimalarial action: effects of weak bases on Plasmodium falciparum
Biochem Pharmacol
(1986) - et al.
The effect of fluorine substitution on the antimalarial activity of tebuquine
Biorg Med Chem Lett
(1996) - et al.
Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum
Biochem Pharmacol
(1992) - et al.
Uptake and efflux by chloroquine resistant Plasmodium falciparum recently isolated in Africa
Acta Tropica
(1994) High resolution autoradiography of malarial parasites treated with 3H chloroquine
Am J Pathol
(1972)- et al.
Identification of the acidic compartment of Plasmodium falciparum infected human erythrocytes as the target for the antimalarial drug chloroquine
EMBO J
(1984)
Antimalarials increase vesicle pH in Plasmodium falciparum
J Cell Biol
(1985)
Antimalarial agents: mechanisms of action
Antimicrob Agents Chemother
(1988)
The effect of fluorine substitution on the metabolism and antimalarial activity of amodiaquine
J Med Chem
(1994)
Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukaemic cells
Mol Pharmacol
(1988)
Cited by (0)
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This work is supported by a Research Programme Grant from the Wellcome Trust.
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B. K. P. is a Wellcome Principal Research Fellow.
Copyright © 1996 Published by Elsevier Inc.