Elsevier

Brain Research

Volume 223, Issue 2, 2 November 1981, Pages 448-454
Brain Research

Voltage-dependent current evoked by dopamine and octopamine in Aplysia

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Abstract

Octopamine and dopamine evoke a slow voltage-dependent inward current in neurons of Aplysia. The responses are present only at depolarized potentials (−40 mV). They are insensitive to changes in potassium, persist after removal of sodium, are not reduced by low chloride solution, and are blocked by cadmium. Because of the similarities in voltage-dependence, time course and ionic sensitivities, the ionic mechanism of the voltage-dependent responses to octopamine and dopamine are concluded to be the same as that of the voltage-dependent response to serotonin reported previously 13.

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T. Pellmar was supported by NIH Fellowship 5F32NS05867 from NINCDS.

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