Opioid peptidesPro-enkephalin intermediates in bovine brain and adrenal medulla: Characterization of immunoreactive peptides related to BAM-22P and peptide F
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Cited by (30)
Opioid receptor function is regulated by post-endocytic peptide processing
2014, Journal of Biological ChemistryCitation Excerpt :A previous study that analyzed the substrate specificity of ECE2 in vitro revealed that among the opioid peptides tested, Dyn B-13, BAM22, BAM18, and peptide E were selectively processed by ECE2 (13), and it is interesting to note that BAM22 and BAM18 were processed to yield BAM12 (13). A number of studies have reported that these peptides are present in vivo (1, 60–64) and that they exhibit differential physiological activities (60, 61, 65). For example, BAM12 has been shown to exhibit a 10-fold lower analgesic effect than BAM22 (60, 61, 65).
Cloning and expression of MRG receptors in macaque, mouse, and human
2005, Molecular Brain ResearchEffects of intrathecal BAM22 on noxious stimulus-evoked c-fos expression in the rat spinal dorsal horn
2004, Brain ResearchCitation Excerpt :The non-opioid effects of BAM22 may be mediated via SNSR for which BAM22 possesses a high affinity [33]. BAM22 is widely distributed in the central nervous system [6,24,31,35,42], including the spinal cord [42,45]. Especially, nerve fiber- and terminal-like processes containing BAM22 have been found to be concentrated in the superficial laminae of the dorsal horn in the lumbar spinal segment [34] where SNSR is putatively located.
Opioid peptides and receptors: Localization, interactions and relationships to other molecules in the rodent brain, especially the hippocampal formation
1989, Progress in Histochemistry and CytochemistryLes endomorphines et les récepteurs des opioïdes
1987, Trait d'Union