[19] Electrophysiological recording from Xenopus oocytes
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Electrophysiological Analysis of Voltage-Gated Ion Channel Modulation by General Anesthetics
2018, Methods in EnzymologyCitation Excerpt :Xenopus oocytes are particularly advantageous because they only express small (100–200 pA) endogenous outward currents in the physiological range of membrane potentials. Detailed procedures for the use of Xenopus oocytes to study ion channel function have been previously described (Stühmer, 1992, 1998). In this section, we focus on specific procedures we have applied to study general anesthetic action on Kv channels, focusing on K-Shaw and Kv1.2.
Combining Mutations and Electrophysiology to Map Anesthetic Sites on Ligand-Gated Ion Channels
2018, Methods in EnzymologyOptogenetic Control of Ca<sup>2 +</sup> and Voltage-Dependent Large Conductance (BK) Potassium Channels
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2015, Journal of Biological Chemistry
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