Original articleIn vitro lymphocyte proliferation by carbamazepine, carbamazepine-10, 11-epoxide, and oxcarbazepine in the diagnosis of drug-induced hypersensitivity
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Cited by (67)
Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia
2020, The Lancet NeurologyCitation Excerpt :Hence, if one drug is not sufficiently effective the other one should be tried. However, if the first drug causes an allergic reaction, caution should be taken because of possible cross-reactivity.62 The drugs should be titrated slowly to the highest dose needed to control the pain with continuous monitoring of side-effects.63
Anticonvulsant agents
2013, Drug-Induced Liver DiseaseActivation of T cells by carbamazepine and carbamazepine metabolites
2006, Journal of Allergy and Clinical ImmunologyCitation Excerpt :This is often problematic because patients hypersensitive to 1 anticonvulsant may develop a hypersensitivity reaction to the alternative medication.29 Zakrzewska and Ivanyi17 have reported that lymphocytes from carbamazepine-hypersensitive patients are not stimulated by oxcarbazepine, and therefore suggested that oxcarbazepine may be suitable as a safe alternative drug treatment. However, clinical data show that approximately 25% of carbamazepine-hypersensitive patients cross-react with oxcarbazepine in vivo.30
Characterization of drug-specific T cells in lamotrigine hypersensitivity
2003, Journal of Allergy and Clinical Immunology
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Dr. J. M. Zakrzewska received a grant from the Welton Foundation and from the Endowment Committee of the British Association of Oral and Maxillofacial Surgeons.