Cell
Volume 74, Issue 4, 27 August 1993, Pages 587-590
MinireviewThe alphas, betas, and kinases of cytokine receptor complexes
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Growth Factors
2020, Atlas of Diagnostic HematologyRegulation of neurokine receptor signaling and trafficking
2012, Neurochemistry InternationalCitation Excerpt :Leukemia inhibitory factor (LIF) and ciliary neurotrophic factor (CNTF) are members of a family of structurally related pluripotent cytokines that have diverse effects on many types of cells and tissues and which can regulate both neuronal survival and phenotypic expression of neuropeptides and neurotransmitters. In addition to CNTF and LIF, this subfamily of neuropoietic cytokines, or neurokines, includes the interleukins IL-6, IL-11, IL-27, IL-37, oncostatin M, and cardiotrophin-1, and bind to an overlapping set of receptor polypeptides (Stahl and Yancopoulos, 1993; Trouillas et al., 2009; Wang et al., 2009). CNTF was identified by its ability to increase the survival of chick ciliary neurons in culture (Barbin et al., 1984).
CNTF, a pleiotropic cytokine: Emphasis on its myotrophic role
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