Elsevier

Molecular Aspects of Medicine

Volume 17, Issue 1, February 1996, Pages 1-3, 5-15, 17-37, 39-65, 67-69, 71-110
Molecular Aspects of Medicine

Apoptosis — Molecular mechanisms and biomedical implications

https://doi.org/10.1016/0098-2997(95)00006-2Get rights and content

Abstract

Apoptosis is a distinct form of cell death of importance in tissue development and homeostasis and in several diseases. This review summarizes current knowledge about the regulation and molecular mechanisms of apoptosis and discusses the potential role of disregulated apoptosis in several major diseases. Finally, we speculate that modulation of apoptosis may be a target in future drug therapy.

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