Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
Volume 1078, Issue 3, 12 July 1991, Pages 411-417
Metabolic stereoisomeric inversion of ibuprofen in mammals
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Your mother was right, washing matters: An alkyne-analog of ibuprofen reveals unwanted reactivity of aromatic compounds with proteins during copper-catalyzed click chemistry
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2020, Journal of Molecular StructureCitation Excerpt :These indicate the possible overlap between the nitrogen N11 and the carbon C1. So a lactamization reaction by an intramolecular attack by the nitrogen lone pair (N11) to carbonyl group carbon (C1) is highly possible [61]. As illustrated in Fig. 3, pregabalin can be degraded directly to prega-L.
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